Primary and Secondary Container Cleaning
This guide provides instructions for performing monthly user maintenance on the Simoa™ HD-1 Analyzer.
For information on using the Analyzer, see the Simoa HD-1 Analyzer User Guide (USER-104-01).
Once a month, the fluid resource containers must be cleaned. The tubing from the containers into the system must be primed with water for 30 minutes before they are primed with buffer for another 30 minutes.
During this procedure, discard all fluids and rinsates according to your company’s waste disposal policies.
The two types of fluid containers are defined as follows:
The tubing leading to the sensor cap is color coded as follows:
NOTE! Do not attempt to perform this procedure when an assay is running. The procedure involves disconnecting the fluid containers, which will prevent the instrument from obtaining the system fluids that are required to perform the assay.
NOTE! Do not reuse the fluids after emptying the containers. Reuse of fluids has been associated with a reduction in data quality.
Priming the System with DI Water
Priming the System with Wash Buffer
Use any glass cleaner that does not contain ammonia.
Wet a paper towel with glass cleaner and then gently wipe down touchscreen. Do not spray glass cleaner directly onto the touchscreen.
Clean exterior instrument surfaces by wiping with a soft, clean cloth moistened with water or 10% ethanol.
WARNING! Turn off the instrument before you perform any of these procedures. The robotic pipettors inside the instrument can injure your hands. Do not insert your hands into the sample bay or the reagent bay if the instrument is turned on.
The system is now ready for use. All normal run maintenance must be performed before the next run (including the Start of Day task). Note the date of completion for record keeping and scheduling the next monthly maintenance procedure.